Shiro to Kuro no Densetsu ~Shin Hyakki Hen~

Black and white compete from the creation of the Universe.

One day a mysterious fire breaks out at a mental hospital. A newspaper reporter tries to uncover the source of the incident and encounters the destruction god "Hyakki" who unleashes havoc on the Earth bringing humanity on the brink of survival. Later reporter has fateful meetings with special people who help to organize rebellion against the fallen God.

[From vndbreview]