X-Change 3

You are Takuya Aihara, the hero/heroine of our story. You've been blessed with a very interesting life: several years ago you were changed a girl through bizarre chemistry accidents, not once but twice. Now as you approach your final year of university with faithful girlfriend Asuka at your side, you almost get nostalgic thinking about those crazy days you spent as a girl.

Until it happens again, that is: that troublesome Kouji, still trying to get your female persona in the sack, secretly gets Asami Satoh to whip up some of the sex-change potion and tricks you into drinking it! It'll be harder than ever for you to change back into your male self this time, but you've got no choice: you have to find a way to change back before your female body becomes permanent. Although Asuka is one of the most understanding women in the world, there's no way she'll stay with you as a girl -- that's just not her thing.

As you start another round of bizarre sexual adventures in your female body, the whole gang is back: your twisted sister Natsumi, who loves to tease you; your smart senpai Asami; even the endlessly experimenting Chisato. With an even richer and more complex game story than last time, you'll have loads of fun exploring college life in your new female body. Where will it all end?

[From Peach Princess]